Vicissitude (noun)
تبدیلی، نشیب و فراز، انقلاب
a change of circumstances or fortune, typically one that is unwelcome or unpleasant.
Example: “her husband’s sharp vicissitudes of fortune”
Vagary (noun)
تغیر، وہم
an unexpected and inexplicable change in a situation or in someone’s behaviour.
Example: “the vagaries of the weather”