Vicissitude (noun) تبدیلی، نشیب و فراز، انقلاب

a change of circumstances or fortune, typically one that is unwelcome or unpleasant.
Example: “her husband’s sharp vicissitudes of fortune”
Vagary (noun) تغیر، وہم

an unexpected and inexplicable change in a situation or in someone’s behaviour.
Example: “the vagaries of the weather”