Deplorable (adjective) خستہ حال، بدقسمتی، قابل رحم

deserving strong condemnation; completely unacceptable.
Example: “children living in deplorable conditions”
Estrange (verb) دور کر دینا، دور کرنا

cause (someone) to be no longer on friendly terms with someone.
Example: “he became estranged from his father”